552 matches
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un studiu realizat de Park și colaboratorii săi (29), efectuat pe șoareci diabetizați tip apoE KO, tratați cu s-RAGE, s-a demonstrat efectul de supresie asupra dezvoltării plăcii aterosclerotice și reducerea reacției inflamatorii. Administrarea de com - plexe solubile s-RAGE a redus reacția inflamatorie și transformarea fibronectinei și a colagenului IV în aria aortei și a rinichiului, efect dependent de doza administrată de s-RAGE și independent de nivelul lipidelor și al glicemiei (29). 6.2.1.1. Interacțiunea cu
Afectarea cardiovasculară în boala renală cronică by Gina Botnariu () [Corola-publishinghouse/Science/91923_a_92418]
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supresie asupra dezvoltării plăcii aterosclerotice și reducerea reacției inflamatorii. Administrarea de com - plexe solubile s-RAGE a redus reacția inflamatorie și transformarea fibronectinei și a colagenului IV în aria aortei și a rinichiului, efect dependent de doza administrată de s-RAGE și independent de nivelul lipidelor și al glicemiei (29). 6.2.1.1. Interacțiunea cu sistemul renină-angiotensină-aldosteron (SRAA) Etiologia complicațiilor cronice hemodinamice interferează cu cele metabolice (glicozilarea proteinelor). Există dovezi clare că acumularea de produși finali de glicoreglare poate determina
Afectarea cardiovasculară în boala renală cronică by Gina Botnariu () [Corola-publishinghouse/Science/91923_a_92418]
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from the loins of Enitharmon, Thou fierce Terror, "Go howl în vain! Smite, smite hîș fetters! smite, O wintry hammers! "Smite, Spectre of Urthona! mock the fiend who drew uș down 425 "From heavens of joy into this deep. Now rage, but rage în vain!" Thus sang the demons of the deep; the Clarions of war blew loud. The Feast redounds, & Crown'd with roses & the circling vine The Enormous Bride & Bridegroom sat; beside them Urizen, With faded radiance sigh'd
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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loins of Enitharmon, Thou fierce Terror, "Go howl în vain! Smite, smite hîș fetters! smite, O wintry hammers! "Smite, Spectre of Urthona! mock the fiend who drew uș down 425 "From heavens of joy into this deep. Now rage, but rage în vain!" Thus sang the demons of the deep; the Clarions of war blew loud. The Feast redounds, & Crown'd with roses & the circling vine The Enormous Bride & Bridegroom sat; beside them Urizen, With faded radiance sigh'd, forgetful of
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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armies, "Sent round hîș heralds secretly commanding to depart "Into the north. Sudden with thunder's sound hîș multitudes 530 "Retreat from the fierce conflict, all the sons of Urizen at once "Must'ring together în thick clouds, leaving the rage of Luvah "To pour its fury on himself & on the Eternal Man. "Sudden down fell they all together into a unknown Space, "Deep, horrible, without End, separated from Beulah, far beneath. 535 "The Man's exteriors are become indefinite, open
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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beautiful gates. The Emanation stood before the Gates of Enitharmon, 560 Weeping; the Daughters of Beulah silent în the Porches Spread her a couch unknown to Enitharmon; here repos'd Jerusalem în slumbers soft, lull'd into silent rest. Terrific rag'd the Eternal wheels of intellect, terrific rag'd The living creatures of the wheels, în the Wars of Eternal life. 565 But perverse roll'd the wheels of Urizen & Luvah, back revers'd Downwards & outwards, consuming în the wars
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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of Enitharmon, 560 Weeping; the Daughters of Beulah silent în the Porches Spread her a couch unknown to Enitharmon; here repos'd Jerusalem în slumbers soft, lull'd into silent rest. Terrific rag'd the Eternal wheels of intellect, terrific rag'd The living creatures of the wheels, în the Wars of Eternal life. 565 But perverse roll'd the wheels of Urizen & Luvah, back revers'd Downwards & outwards, consuming în the wars of Eternal Death. VALA Night the [Second] Rising
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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Looms erected First spun, then wove the Atmospheres; there the Spider & Worm Plied the wing'd shuttle, piping shrill thro' all the list'ning threads; Beneath the Caverns roll the weights of lead & spindles of iron, The enormous warp & woof rage direful în the affrighted deep. 150 While far into the vast unknown the strong wing'd Eagles bend Their venturous flight în Human forms distinct; thro' darkness deep They bear the woven draperies; on golden hooks they hang abroad The
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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heard the Voice & fled, swift aș the winter's setting sun. "And now the Human Blood foam'd high. I saw that Luvah & Vala 95 "Went down the Human Heart, where Paradise & its joys abounded, "În jealous fears, în fury & rage, & flames roll'd round their fervid feet, "And the vast form of Nature like a Serpent play'd before them; "And aș they went, în folding fires & thunders of the deep, "Vala shrunk în like the dark șea that leaves
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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quite, but let 185 "A little shadow, but a little showery form of Enion "Be near thee, loved Terror; let me still remain & then do thou "Thy righteous doom upon me; only let me hear thy voice. "Driven by thy rage I wander like a cloud into the deep "Where never yet Existence came; there losing all my life 190 "I back return weaker & weaker; consume me not away "În thy great wrath; tho' I have sinned, tho' I have rebell
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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not been. "Make not the thing that loveth thee a tear wiped away." Tharmas replied, riding on storms, hîș voice of Thunder roll'd: 195 "Image of grief, thy fading lineaments make my eyelids fail. "What have I done? both rage & mercy are alike to me; "Looking upon thee, Image of faint waters, I recoil "From my fierce rage into thy semblance. Enion, return. "Why does thy piteous face Evanish like a rainy cloud 200 "Melting, a shower of falling tears
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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hîș voice of Thunder roll'd: 195 "Image of grief, thy fading lineaments make my eyelids fail. "What have I done? both rage & mercy are alike to me; "Looking upon thee, Image of faint waters, I recoil "From my fierce rage into thy semblance. Enion, return. "Why does thy piteous face Evanish like a rainy cloud 200 "Melting, a shower of falling tears, nothing but tears! Enion, "Substanceless, voiceless, weeping, vanish'd, nothing but tears! Enion, "Art thou for ever vanish
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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face Evanish like a rainy cloud 200 "Melting, a shower of falling tears, nothing but tears! Enion, "Substanceless, voiceless, weeping, vanish'd, nothing but tears! Enion, "Art thou for ever vanish'd from the wat'ry eyes of Tharmas? "Rage, Rage shall never from my bosom: winds & waters of woe "Consuming all, to the end consuming. Love and Hope are ended." 205 For now no more remain'd of Enion în the dismal air, Only a voice eternal wailing în the
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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love & pity? "Ah, Enion! Ah, Enion! Ah, lovely, lovely Enion! "How is this? All my hope is gone! for ever fled! 10 Like a famish'd Eagle, Eyeless, raging în the vast expanse, "Incessant tears are now my food, incessant rage & tears. "Deathless for ever now I wander seeking oblivion "În torrents of despair: în vain; for if I plunge beneath, "Stifling I live: If dash'd în pieces from a rocky height, 15 "I reunite în endless torment; would I
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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a rocky height, 15 "I reunite în endless torment; would I had never risen "From death's cold sleep beneath the bottom of the raging Ocean. "And cannot those who once have lov'd ever forget their Love? "Are love & rage the same passion? they are the same în me. "Are those who love like those who died, risen again from death, 20 "Immortal în immortal torment, never to be deliver'd? "Is it not possible that one risen again from
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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pangs of heart: "Tharmas, I know thee: how are we alter'd, our beauty decay'd! 80 "But still I know thee, tho' în this horrible ruin whelm'd. "Thou, once the mildest son of heaven, art now become a Rage, "A terror to all living things; think not that I am ignorant "That thou art risen from the dead, or that, my power forgot, "I slumber here în weak repose. I well remember the Day, 85 "The day of terror
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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I issued into the air, divided from Enitharmon. "I howl'd în sorrow. I beheld thee rotting upon the Rocks. "I, pitying, hover'd over thee; I protected thy ghastly corse "From Vultures of the deep; then wherefore shouldst thou rage 110 "Against me who thee guarded în the night of death from harm?" Tharmas replied: "Art thou Urthona, My friend, my old companion "With whom I liv'd în happiness before that deadly night "When Urizen gave the horses of
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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billows & waves pass over hîm, "The șea encompasses hîm & monsters of the deep are hîș companions. 135 "Dreamer of furious oceans, cold sleeper of weeds & shells, "Thy Eternal form shall never renew, my uncertain prevails against thee. "Yet tho' I rage, God over all, A portion of my Life "That în Eternal fields în comfort wander'd with my flocks "At noon & laid her head upon my wearied bosom at night, 140 "She is divided. She is vanish'd, even like
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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Eyes were open'd on the Abyss, 40 The horrid trumpets of the deep bellow'd with bitter blasts. The Enormous Demons woke & howl'd around the new born King, Crying, "Luvah, King of Love, thou art the King of rage & death." Urizen cast deep darkness round hîm; raging, Luvah pour'd The spears of Urizen from Chariots round the Eternal tent. 45 Discord began, then yells & cries shook the wide firmament: "Where is sweet Vala, gloomy prophet? where the lovely
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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whose souls are flames of fire. "But now the times return upon thee. Enitharmon's womb "Now holds thee, soon to issue forth. Sound, Clarions of war! "Call Vala from her close recess în all her dark deceit, 65 "Then rage on rage shall fierce redound ouț of her crystal quiver." Șo sung the Demons round red Orc & round faint Enitharmon. Sweat & blood stood on the limbs of Los în globes; hîș fiery Eyelids Faded; he rouz'd, he siez'd
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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are flames of fire. "But now the times return upon thee. Enitharmon's womb "Now holds thee, soon to issue forth. Sound, Clarions of war! "Call Vala from her close recess în all her dark deceit, 65 "Then rage on rage shall fierce redound ouț of her crystal quiver." Șo sung the Demons round red Orc & round faint Enitharmon. Sweat & blood stood on the limbs of Los în globes; hîș fiery Eyelids Faded; he rouz'd, he siez'd the wonder
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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down, binding around hîș limbs The accursed chain. O how bright Enitharmon howl'd & cried Over her son! Obdurate, Los bound her loved Joy. The hammer of Urthona smote the rivets în terror, of brass 105 Tenfold; the Demon's rage flam'd tenfold forth, rending, Roaring, redounding, Loud, Loud, Louder & Louder, & fir'd The darkness, warring with the waves of Tharmas & Snows of Urizen. Crackling the flames went up with fury from the immortal demon. Surrounded with flames the Demon
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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around the Demon, going forth & returning. At hîș enormous call they flee into the heavens of heavens And back return with wine & food, or dive into the deeps 120 To bring the thrilling joys of sense to quell hîș ceaseless rage. Hîș eyes, the lights of hîș large soul, contract or else expand: Contracted they behold the secret of the infinite mountains, The veins of gold & silver & the hidden things of Vala, Whatever grows from its pure bud or breathes a
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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iron rock & grew a chain beneath the Earth Even to the Center, wrapping round the Center; & the limbs Of Orc entering with fibres become one with hîm, a living Chain 170 Sustained by the Demon's life. Despair & Terror & Woe & Rage Inwrap the Parents în cold clouds aș they bend howling over The terrible boy, till fainting by hîș side, the Parents fell. Not long they lay; Urthona's spectre found herbs of the pit. Rubbing their temples, he reviv'd
by William Blake [Corola-publishinghouse/Science/1122_a_2630]
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repose, "And to reveal myself before thee în a form of wisdom. "Yet thou dost laugh at all these tortures, & this horrible place: 60 "Yet throw thy limbs these fires abroad that back return upon thee "While thou reposest, throwing rage on rage, feeding thyself "With visions of sweet bliss far other than this burning clime. "Sure thou art bath'd în rivers of delight, on verdant fields "Walking în joy, în bright Expanses sleeping on bright clouds 65 "With visions
by William Blake [Corola-publishinghouse/Science/1122_a_2630]